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Author:Eyasu Makonnen , Anteneh Belete
Data Source:[J].Trials(IF 2.206), 2017, Vol.18 (1)Springer
Abstract:Just over 2 years ago on 20 May 2014, we celebrated the first International Clinical Trial Day (ICTD) in Ethiopia at the College of Health Sciences, Addis Ababa University. The main aim of the celebration was to express solidarity with clinical researchers, particularly clinical ...
Author:Eyasu Makonnen , Tesfaye Awas
Data Source:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2017, Vol.17 (1)Springer
Abstract:Malaria is a major public health problem in the world which is responsible for death of millions particularly in sub-Saharan Africa. Today, the control of malaria has become gradually more complex due to the spread of drug-resistant parasites. Medicinal plants are the unquestiona...
Author:... Kelbessa Urga , Wondwossen Ergete , Eyasu Makonnen
Data Source:[J].BMC Research Notes, 2017, Vol.10 (1)Springer
Abstract:In southeast Ethiopia, people locally use the roots of Gnidia stenophylla Gilg (Thymelaeaceae) to cure malaria and other diseases with no literature evidence substantiating its safety. The aim of this study was, therefore, to investigate the safety of the aqueous root extract of ...
Author:Biniyam Girma , Getnet Yimer , Eyasu Makonnen
Data Source:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2015, Vol.15 (1)Springer
Abstract:Abstract(#br) Background(#br)Cancer as a multistage process can be reversed or blocked by using chemopreventive agents. Colon cancer chemoprevention has been widely investigated using cyclooxygenase inhibitors and many other chemicals of synthetic or natural origin. This par...
Author:Eyasu Makonnen , Michiaki Kubo
Data Source:[J].BMC Genomics(IF 4.397), 2016, Vol.17 (1)Springer
Abstract:Abstract(#br) Background(#br)Drug-induced liver injury (DILI) is a well-recognized adverse event of anti tuberculosis drugs (ATD) possibly associated with genetic variations. The objective of this study was to perform genome-wide association study (GWAS) to identify genetic ...
Author:Eyasu Makonnen , Yelamtsehay Mekonnen ...
Data Source:[J].BMC Complementary and Alternative Medicine(IF 2.082), 2015, Vol.15 (1)Springer
Abstract:Abstract(#br) Background(#br) Moringa stenopetala has been used in traditional health systems to treat diabetes mellitus. The aim of this study was to investigate the antidiabetic activity of aqueous ethanol and n-butanol fraction of Moringa stenopetala leaves in streptozoto...
Author:Eyasu Makonnen , Leif Bertilsson
Data Source:[J].European Journal of Clinical Pharmacology(IF 2.741), 2018, Vol.74 (7), pp.903-911Springer
Abstract:Abstract(#br) Background and objectives(#br)N-acetyltransferase 2 (NAT2) metabolize several drugs including isoniazid. We investigated the effect of genotype, geographical difference, and smoking habit on NAT2 phenotype in Ethiopians.(#br) Methods(#br)Genotyping for NAT2 191G > A...
Author:Eyasu Makonnen , Tadesse Eguale ...
Data Source:[J].Journal of Ethnopharmacology(IF 2.755), 2012, Vol.143 (2), pp.469-474Elsevier
Abstract:Abstract(#br)Ethnopharmacological relevance(#br)The leaves of Achyranthes aspera L . (Amarenthacea) has been used traditionally for the treatment of wound in various parts of Ethiopia. However, the plant has not been explored scientifically for its wound healing activity. Therefo...
Author:Birhanetensay Masresha , Eyasu Makonnen , Asfaw Debella
Data Source:[J].Journal of Ethnopharmacology(IF 2.755), 2012, Vol.142 (1), pp.201-205Elsevier
Abstract:Abstract(#br)Ethnopharmacological relevance(#br)Ocimum suave has been used in the Ethiopian traditional medicine to relieve pain, fever, inflammation and other disease conditions.(#br)Aim of the study(#br)The aim of the present study was to investigate the anti-inflammatory activ...
Author:Eyasu Makonnen , Getachew Aderaye ...
Data Source:[J].Liver International(IF 3.87), 2017, Vol.37 (1), pp.132-140Wiley
Abstract:Abstract(#br)Background & Aims(#br)The occurrence of drug‐induced liver injury ( DILI ) is a major issue in all phases of drug development. To identify novel biomarker candidates associated with DILI , we utilised an affinity proteomics strategy, where antibody suspension be...

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