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Author:Helfand Mark , Tunis Sean ...
Data Source:[J].Clinical and Translational Science (Online), 2011, Vol.4 (3), pp.188-98PubMed
Abstract:Clinical research needs to be more useful to patients, clinicians, and other decision makers. To meet this need, more research should focus on patient-centered outcomes, compare viable alternatives, and be responsive to individual patients' preferences, needs, pathobiology, setti...
Author:Helfand Mark , Balshem Howard
Data Source:[J].Journal of Clinical Epidemiology, 2009, Vol.63 (5), pp.484-90PubMed
Abstract:This article describes some of the fundamental principles that have been developed to guide the work of producing comparative effectiveness reviews (CERs).;;We briefly describe the role stakeholders play in providing important insights that inform the evidence-gathering process, ...
Author:Helfand Mark
Data Source:[J].Health Affairs(IF 4.641), 2005, Vol.24 (1), pp.123-7PubMed
Abstract:This Perspective describes the advantages of using systematic evidence reviews in preferred drug deliberations. By involving decisionmakers in defining the scope, evidence reports help focus deliberations on clinically important questions and reduce the likelihood of bias. They d...
Author:Helfand Mark
Data Source:[J].Medical Decision Making(IF 2.89), 2005, Vol.25 (1), pp.8-10PubMed
Author:Helfand Mark
Data Source:[J].Medical Care(IF 3.227), 2005, Vol.43 (7 Suppl), pp.33-43PubMed
Abstract:There is a pressing need for guidance on how to incorporate economic information into evidence-based decision-making. Such guidance should take account of the quality and relevance of economic evaluations.;;To summarize lessons learned in integrating information from decision ana...
Author:Helfand Mark
Data Source:[J].Annals of Internal Medicine, 2004, Vol.140 (2), pp.128-41PubMed
Abstract:Subclinical thyroid dysfunction is a risk factor for developing symptomatic thyroid disease. Advocates of screening argue that early treatment can prevent serious morbidity in individuals who are found to have laboratory evidence of subclinical thyroid dysfunction.;;This article ...

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