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Author:Wang Qingde , Yang Huan ...
Data Source:[J].Arteriosclerosis, Thrombosis, and Vascular Biology(IF 6.338), 2015, Vol.35 (12), pp.2579-2593The Royal Society
Abstract:Objective— Endoluminal vascular interventions such as angioplasty initiate a sterile inflammatory response resulting from local tissue damage. This response drives the development of intimal hyperplasia (IH) that, in turn, can lead to arterial occlusion. We hypothesized that...
Author:... Zhang Jinxiang , Wang Qingde , Billiar Timothy R
Data Source:[J].Scientific reports(IF 2.927), 2016, Vol.6, pp.20248PubMed
Abstract:Excessive inflammation resulting from activation of the innate immune system significantly contributes to ischemia/reperfusion injury (IRI). Inflammatory reactions in both IRI and infections share the same signaling pathways evoked by danger/pathogen associated molecular pattern ...
Author:王庆德 , 杨述华 , 杨操 ...
Data Source:[J].中国修复重建外科杂志, 2007, (10), pp.1128-1132CNKI
Abstract:目的建立人骨髓间充质干细胞(human marrow mesenchymal stem cells,hMSCs)体外低氧培养及向成骨细胞分化的生物模型,研究其生物学特征,为骨组织工程提供实验依据。方法采用人淋巴细胞分离液分离健康成人hMSCs,DMEM-LG(...
Cited Times:8Download Times:224
Author:Wang Qingde , Scott Melanie J
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (2), pp.151-7PubMed
Abstract:Viral infection in the liver, including hepatitis B virus (HBV) and hepatitis C virus (HCV) infection, is a major health problem worldwide, especially in developing countries. The infection triggers a pro-inflammatory response in patients that is crucial for host defense. Recent ...
Author:... Lu Ben , Wang Qingde , Billiar Timothy R
Data Source:[J].The Journal of biological chemistry, 2016, Vol.291 (29), pp.15093-107PubMed
Abstract:The sensing of double-stranded RNA (dsRNA) in the liver is important for antiviral defenses but can also contribute to sterile inflammation during liver injury. Hepatocytes are often the target of viral infection and are easily injured by inflammatory insults. Here we sought...
Author:王庆德 , 杨述华 , 杨操 ...
Data Source:[J].华中科技大学学报(医学版), 2008, (01), pp.55-58+72CNKI
Abstract:目的探讨低氧对人间充质干细胞(hMSCs)分化为成骨细胞的影响,为骨组织工程学提供实验依据。方法根据培养氧浓度及培养液类型随机分为4组:正常氧组(n)(20%O2+DMEM-LG),低氧组(h)(1%O2+DMEM-LG),正常氧成骨诱导组(nos)(20%O...
Cited Times:4Download Times:209
Author:张金龙 , 王庆德 , 张顺堂
Data Source:[J].黄金学报, 2000, (03), pp.207-211CNKI
Abstract:本文详细分析了金矿尾矿的组分构成并与常用陶瓷原料作了对比分析 ,认为这种尾矿经除杂后可以作为陶瓷墙地砖生产中的优质长石代用原料 .尾矿经螺旋溜槽分级 (重选 )、弱磁选、强磁选、浮选等工艺 ...
Cited Times:8Download Times:84
Author:Sharma Rohit B , Wang Qingde , Khillan Jaspal S
Data Source:[J].Biochemical and biophysical research communications, 2013, Vol.436 (4), pp.625-31PubMed
Abstract:Solid tumors contain a rare population of cancer stem cells (CSCs) that are responsible for relapse and metastasis. The existence of CSC however, remains highly controversial issue. Here we present the evidence for putative CSCs from mammary tumors amplified by vitamin A/retinol ...
Author:Wang Qingde , Yuan Hong
Data Source:[J].Arteriosclerosis, thrombosis, and vascular biology, 2013, Vol.33 (8), pp.1920-7PubMed
Abstract:Circulating angiogenic cells play an essential role in angiogenesis but are dysfunctional in diabetes mellitus characterized by excessive oxidative stress. We hypothesize that oxidative stress-mediated upregulation of thrombospondin-2 (TSP-2), a potent antiangiogenic protein, con...

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