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Author:... Yuan Ying , Cui Shusen , Yao Dengbing
Data Source:[J].BMC neuroscience(IF 3), 2017, Vol.18 (1), pp.30PubMed
Abstract:Wallerian degeneration (WD) in injured peripheral nerves is associated with a large number of up- or down-regulated genes, but the effects of these changes are poorly understood. In our previous studies, we reported some key factors that are differentially expressed to activ...
Author:Yao Dengbing , Li Meiyuan ...
Data Source:[J].Neural regeneration research(IF 0.144), 2012, Vol.7 (17), pp.1285-92PubMed
Abstract:Wallerian degeneration is an important area of research in modern neuroscience. A large number of genes are differentially regulated in the various stages of Wallerian degeneration, especially during the early response. In this study, we analyzed gene expression in early Wal...
Author:... Zhang Yuanyuan , Kido Hiroshi , Yao Dengbing
Data Source:[J].PloS one(IF 3.73), 2015, Vol.10 (3), pp.e0119936PubMed
Abstract:Carnitine palmitoyltransferase II (CPT II) deficiency is one of the most common causes of fatty acid oxidation metabolism disorders. However, the molecular mechanism between CPT2 gene polymorphisms and metabolic stress has not been fully clarified. We previously reported tha...
Author:Yao Dengbing , Wang Li ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (2), pp.123-30PubMed
Abstract:Worldwide incidence of hepatocellular carcinoma (HCC) is steadily increasing, highlighting its status as a public health concern, particularly due to its significant association with other comorbidities, such as diabetes. However, nonalcoholic fatty liver disease (NAFLD) has emer...
Author:沈爱国 , 姚登兵 , 丁斐 ...
Data Source:[J].神经解剖学杂志, 2003, (01), pp.17-22CNKI
Abstract:为了探讨周围神经Schwann细胞中不同β1,4半乳糖基转移酶-1(β-1,4-GalT-I)表达水平对神经元轴突生长的影响,本实验首先构建了正、反义β-1,4-GalT-I表达质粒,然后将构建的不同浓度的正、反义表达质粒超表达于...
Cited Times:8Download Times:52
Author:于彬 , 王勇军 , 周松林 ...
Data Source:[J].交通医学, 2010, (06), pp.599-601CNKI
Abstract:目的:研究大鼠坐骨神经缺损后损伤近端神经组织中microRNA(miRNA)的表达变化。方法:采用miRNA芯片检测神经缺损0h(对照组),3h和6h(实验组)损伤近端神经组织miRNA的表达情况,应用real time Taqman PCR对芯片结果进行验证...
Cited Times:2Download Times:95
Author:王勇军 , 汤欣 , 于彬 ...
Data Source:[J].交通医学, 2010, (06), pp.589-591+595+740CNKI
Abstract:目的:采用基因芯片技术结合信号传递调控网络(Signal-Flow)分析技术,探讨坐骨神经缺损近端神经组织早期分子信号调控机理。方法:SD大鼠坐骨神经缺损0h、0.5h、1h、3h、6h和9h后,取0.5cm近端神经组织进行mRNA芯片检测...
Cited Times:1Download Times:76
Author:LI ShiYing , YU Bin , WANG YongJun, YAO DengBing, ZHANG ZhanHu & GU XiaoSong * Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong 210063, China
Data Source:[J].Science China(Life Sciences)(IF 2.024), 2011, (09), pp.806-812CNKI
Abstract:The peripheral nervous system is able to regenerate after injury, and regeneration is associated with the expression of many genes and proteins. MicroRNAs are evolutionarily conserved, small, non-coding RNA molecules that regulate gene expression at the level of translation. In t...
Cited Times:-Download Times:28
Author:Yao Dengbing , Li Meiyuan ...
Data Source:[J].Neuroscience bulletin, 2013, Vol.29 (3), pp.321-32PubMed
Abstract:Wallerian degeneration (WD) remains an important research topic. Many genes are differentially expressed during the process of WD, but the precise mechanisms responsible for these differentiations are not completely understood. In this study, we used microarrays to analyze the ex...

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