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Author:Yao Dengbing , Shi Jianhua ...
Data Source:[J].Life Sciences(IF 2.555), 2004, Vol.76 (24), pp.2763-2772Elsevier
Abstract:Abstract(#br)Hepatic fibrosis occurs after many years of iron overload in liver. An effective iron deposition model induced by ferric nitrilotriacetate (FeNTA) in cultured rat hepatocytes was assumed. It has been shown that treatment of rat hepatocytes with FeNTA lead to oxidativ...
Author:... Yuan Ying , Cui Shusen , Yao Dengbing
Data Source:[J].BMC neuroscience(IF 3), 2017, Vol.18 (1), pp.30PubMed
Abstract:Wallerian degeneration (WD) in injured peripheral nerves is associated with a large number of up- or down-regulated genes, but the effects of these changes are poorly understood. In our previous studies, we reported some key factors that are differentially expressed to activ...
Author:Yao Dengbing , Wang Li ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (2), pp.123-30PubMed
Abstract:Worldwide incidence of hepatocellular carcinoma (HCC) is steadily increasing, highlighting its status as a public health concern, particularly due to its significant association with other comorbidities, such as diabetes. However, nonalcoholic fatty liver disease (NAFLD) has emer...
Author:沈爱国 , 姚登兵 , 丁斐 ...
Data Source:[J].神经解剖学杂志, 2003, (01), pp.17-22CNKI
Abstract:为了探讨周围神经Schwann细胞中不同β1,4半乳糖基转移酶-1(β-1,4-GalT-I)表达水平对神经元轴突生长的影响,本实验首先构建了正、反义β-1,4-GalT-I表达质粒,然后将构建的不同浓度的正、反义表达质粒超表达于...
Cited Times:8Download Times:52
Author:于彬 , 王勇军 , 周松林 ...
Data Source:[J].交通医学, 2010, (06), pp.599-601CNKI
Abstract:目的:研究大鼠坐骨神经缺损后损伤近端神经组织中microRNA(miRNA)的表达变化。方法:采用miRNA芯片检测神经缺损0h(对照组),3h和6h(实验组)损伤近端神经组织miRNA的表达情况,应用real time Taqman PCR对芯片结果进行验证...
Cited Times:2Download Times:95
Author:王勇军 , 汤欣 , 于彬 ...
Data Source:[J].交通医学, 2010, (06), pp.589-591+595+740CNKI
Abstract:目的:采用基因芯片技术结合信号传递调控网络(Signal-Flow)分析技术,探讨坐骨神经缺损近端神经组织早期分子信号调控机理。方法:SD大鼠坐骨神经缺损0h、0.5h、1h、3h、6h和9h后,取0.5cm近端神经组织进行mRNA芯片检测...
Cited Times:1Download Times:76
Author:LI ShiYing , YU Bin , WANG YongJun, YAO DengBing, ZHANG ZhanHu & GU XiaoSong * Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong 210063, China
Data Source:[J].Science China(Life Sciences)(IF 2.024), 2011, (09), pp.806-812CNKI
Abstract:The peripheral nervous system is able to regenerate after injury, and regeneration is associated with the expression of many genes and proteins. MicroRNAs are evolutionarily conserved, small, non-coding RNA molecules that regulate gene expression at the level of translation. In t...
Cited Times:-Download Times:28
Author:姚登兵 , 王勇军 , 顾晓松
Data Source:[J].交通医学, 2013, (06), pp.580-584+735
Abstract:目的:运用基因芯片和蛋白芯片技术及生物信息学分析,系统分析大鼠坐骨神经损伤后远端神经组织Wallerian溃变的差异表达基因和蛋白,从基因和蛋白水平探讨Wallerian溃变的分子机制。方法:建立大鼠损伤坐骨神...
Author:张焕焕 , 高楠楠 , 石玲玉 ...
Data Source:[J].交通医学, 2017, (02), pp.103-107+111
Abstract:目的:研究TLR4(Toll-like receptor 4)在大鼠坐骨神经损伤后,Wallerian溃变过程中的作用,为周围神经损伤修复与再生的研究提供实验依据。方法:制备大鼠损伤坐骨神经模型;利用修饰过的TLR4基因过表达质粒导入大鼠损...

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