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Author:Yim Ling Mak , Leanne Lai Hang Chan ...
Data Source:[J].Molecular Neurobiology(IF 5.471), 2017, Vol.54 (7), pp.5590-5603Springer
Abstract:Ciguatera fish poisoning (CFP) is a common human food poisoning caused by consumption of ciguatoxin (CTX)-contaminated fish affecting over 50,000 people worldwide each year. CTXs are classified depending on their origin from the Pacific (P-CTXs), Indian Ocean (I-CTXs), and C...
Author:Yim Ling Mak , Jing Li ...
Data Source:[J].Journal of Hazardous Materials(IF 3.925), 2017, Vol.321, pp.782-790Elsevier
Abstract:Abstract(#br)Ciguatoxins (CTXs) are natural biotoxins produced by benthic dinoflagellates of the genus Gambierdiscus , which are bioaccumulated and biotransformed along food chains in coral ecosystems. They are neurotoxins that activate voltage-gated sodium channels and disrupt i...
Author:Yim Ling Mak , Chung-Kuang Lu ...
Data Source:[J].Harmful Algae(IF 2.901), 2017, Vol.67, pp.107-118Elsevier
Abstract:Abstract(#br)Recent molecular phylogenetic studies of Gambierdiscus species flagged several new species and genotypes, thus leading to revitalizing its systematics. The inter-relationships of clades revealed by the primary sequence information of nuclear ribosomal genes (rDN...
Author:Yim Ling Mak , Leo Lai Chan ...
Data Source:[J].Molecular Neurobiology(IF 5.471), 2018, Vol.55 (8), pp.6769-6787Springer
Abstract:Abstract(#br)Consumption of fish containing ciguatera toxins or ciguatoxins (CTXs) causes ciguatera fish poisoning (CFP). In some patients, CFP recurrence occurs even years after exposure related to CTXs accumulation. Pacific CTX-1 (P-CTX-1) is one of the most potent natural subs...
Author:Yim Ling Mak , Steve L. Morton ...
Data Source:[J].Harmful Algae(IF 2.901), 2017, Vol.68, pp.206-216Elsevier
Abstract:Abstract(#br)This study confirms the presence of the toxigenic benthic dinoflagellates Gambierdiscus belizeanus and Ostreopsis spp. in the central Red Sea. To our knowledge, this is also the first report of these taxa in coastal waters of Saudi Arabia, indicating the potenti...
Author:Yim Ling Mak , Paul Kwan Sing Lam ...
Data Source:[J].Toxicon(IF 2.924), 2014, Vol.77, pp.16-25Elsevier
Abstract:Abstract(#br)Saxitoxin (STX) is the most potent paralytic shellfish poisoning toxin in crustaceans and molluscs, and is known to cause intoxication to humans and marine animals due to its neurotoxicity. However, the extent of its early developmental toxicity to marine species rem...
Author:Yim Ling Mak , Leo Lai Chan ...
Data Source:[J].Harmful Algae(IF 2.901), 2014, Vol.34, pp.56-68Elsevier
Abstract:Abstract(#br)Ciguatera is a serious seafood poisoning syndrome caused by the consumption of ciguatoxin-contaminated finfish from tropical and subtropical regions. This study examined the community structure of ciguatera-associated dinoflagellates and the distribution pattern...

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