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Author:Axley Page , Ahmed Zunirah , Ravi Sujan ...
Data Source:[J].Journal of clinical and translational hepatology, 2018, Vol.6 (1), pp.79-84PubMed
Abstract:Hepatocellular carcinoma (HCC) is a leading cause of liver-related death worldwide. Hepatitis C virus (HCV) infection is a major cause of advanced hepatic fibrosis and cirrhosis, with significantly increased risk for development of HCC. The morbidity and mortality of HCV-related ...
Author:Daher Saleh , Massarwa Muhammad , Benson Ariel A ...
Data Source:[J].Journal of clinical and translational hepatology, 2018, Vol.6 (1), pp.69-78PubMed
Abstract:... Due to the poor prognosis of patients with HCC, newer treatments are needed with several being in development, either in pre-clinical or clinical studies. In this review article, we provide an update on the current and future medical and surgical management of HCC.
Author:Xu Xiaobo , Chen Yiling , Zhang Ruiqing ...
Data Source:[J].Journal of clinical and translational hepatology, 2018, Vol.6 (1), pp.85-88PubMed
Abstract:Locoregional therapy is playing an increasingly important role in the non-surgical management of hepatocellular carcinoma (HCC). The novel technique of non-thermal electric ablation by nanosecond pulsed electric field has been recognized as a potential locoregional methodology fo...
Author:Kralj Dominik , Jukić Lucija Virović , Stojsavljević Sanja ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (1), pp.66-75PubMed
Abstract:... Over time, it has been shown that the frequent coexistence of these two conditions is not coincidental, since many epidemiological, clinical, and experimental studies have indicated HCV to be strongly associated with liver steatosis and numerous metabolic derangements. Here, ...
Author:Cosarderelioglu Caglar , Cosar Arif M , Gurakar Merve ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (1), pp.47-53PubMed
Abstract:A severe and common pulmonary vascular complication of liver disease is hepatopulmonary syndrome (HPS). It is a triad of liver dysfunction and/or portal hypertension, intrapulmonary vascular dilatations, and increased alveolar-arterial oxygen gradient. Prevalence varies according...
Author:Pakala Tina , Molina Marco , Wu George Y
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (1), pp.39-46PubMed
Abstract:... The increased emigration of populations from endemic areas where prevalence rates are as high as 5-10% and the relatively quiescent clinical course of CE pose challenges for accurate and timely diagnoses. Upon infection with CE, cyst formation mainly occurs in the liver (70%)...
Author:Kumar Ashish , Gupta Varun , Sharma Praveen ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (1), pp.26-31PubMed
Abstract:... Whether IL-28b genotypes also influence other nontreatment related clinical parameters is unclear.;;Patients with HCV-related chronic liver diseases who attended our department during 2012-2014 were retrospectively analyzed. The single nucleotide polymorphisms (SNPs) of rs129...
Author:Tama Maher , Naylor Paul , Patel Suhag ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (1), pp.12-9PubMed
Abstract:Evaluation of advanced fibrosis in patients with hepatitis C virus (HCV) infection is used to facilitate decisions on treatment strategy and to initiate additional screening measures. Unfortunately, most studies have predominately Caucasian (Cau) patients and may not be as r...
Author:Taniguchi Miki , Tasaka-Fujita Megumi , Nakagawa Mina ...
Data Source:[J].Journal of clinical and translational hepatology, 2016, Vol.4 (1), pp.5-11PubMed
Abstract:The hepatitis C virus (HCV) genotype 1b is known to exhibit treatment resistance with respect to interferon (IFN) therapy. Substitution of amino acids 70 and 91 in the core region of the 1b genotype is a significant predictor of liver carcinogenesis and poor response to pegy...

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